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INREBIC® (fedratinib) is a prescription medicine used to treat adults with certain types of myelofibrosis (MF). It is not known if INREBIC is safe and effective in children.

Resources and Support

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    Celgene Patient Support® — a single source for access support

    Celgene Patient Support

     

    Celgene Patient Support® provides:

    • A single specialist assigned to help patients in your geographic area
    • Assistance with understanding patient insurance coverage for INREBIC
    • Information about financial assistance for INREBIC

    Financial assistance

    Depending on your insurance situation, there are programs and organizations that may help pay for INREBIC.

     

    Celgene commercial co-pay program

    For eligible patients with commercial or private insurance (including healthcare exchanges),* co-pay responsibility for INREBIC is reduced to $25 (subject to annual benefit limit).

     

    Celgene Patient Assistance Program (PAP)

    For qualified patients who are uninsured or underinsured, INREBIC may be available at no cost.

     

    Independent third-party organizations

    For patients who are unable to afford their medication (including patients with Medicare, Medicaid, or other government-sponsored insurance),independent third-party organizations may be able to help.

     

    *Eligibility requirements and restrictions apply. Please see Terms and Conditions on the Celgene Patient Support® website. Patients must meet specified financial and insurance eligibility requirements to qualify for assistance. Please see Eligibility Requirements on the Celgene Patient Support® website. Financial and medical eligibility requirements may vary by organization.

    Learn More About Financial Assistance

    Enrolling in
    Celgene Patient Support®

    There are 3 simple ways to enroll in Celgene Patient Support®

     

    Enroll online

    Enroll online at www.celgenepatientsupport.com

     

    Call 1-800-931-8691

    Call us at 1-800-931-8691, Monday–Friday, 8 AM–8 PM ET (translation services available).

     

    Email or fax the enrollment form

    E-mail a completed enrollment form to patientsupport@celgene.com or fax 1-800-822-2496.

    Talking about MF with your doctor begins with some crucial questions

    It’s important to be upfront about what you’re experiencing. Honest communication with your care team can help you make informative choices about your health. It also helps to build a strong partnership. A strong team can mean more support for you.

    Try using these questions to get the information you need. Consider taking notes as you hear the answers to refer to after your appointment.

    Talk about your symptoms.

    • I’m on treatment, but I’m still feeling tired, have pain, etc.
    • I have symptoms such as nausea, diarrhea, itchiness, etc. Is there anything you can suggest to help manage them?
    • Be as specific and open as you can with your HCP by asking questions and communicating specific information about the symptoms you might be experiencing
    • Should I expect to feel better or is this just how it’s going to be?

    Ask about your options.

    • What are my treatment options?
    • What do you consider when determining the appropriate treatment
      for me?

    Ask about INREBIC.

    • What are the side effects with INREBIC that I should be aware of?
    • Are there any side effects that I experience which signal I call you
      immediately?
    • Does INREBIC interact with any other medications I’m currently
      taking?
    • What can I expect when taking INREBIC?

    Ask other important questions about INREBIC.

    • Will my health insurance pay for INREBIC?
    • What if my INREBIC prescription is denied by my health insurance?
    • Does INREBIC have a patient support program?
    • How do I get my INREBIC prescription through a specialty pharmacy?

    Ask loved ones for help.

    • Would you come with me to my appointments?
    • Can you help me prepare for my appointments?
    • Can you take notes while I listen to what the doctor says?
    • Will you help me remember to take my medication?
    • Can you help me track or remind me to track my symptoms?
    • Can you help me discuss or remind me to discuss my questions
      with my doctor?

    MF Organizations and Advocacy Groups

    This list of independent organizations is provided as a resource for obtaining support and information related to MF.

    This list does not indicate endorsement by Bristol-Myers Squibb Company of an organization or its communications.

    Get Patient Brochure

    Keep the possible benefits of INREBIC top of mind. Download a patient brochure about INREBIC to refer to when you have any questions.

    Download

    Inrebic patient brochure

    Reaching out to others

    Living with myelofibrosis may be particularly stressful for patients. They might not know how to talk about it, and it may be hard to know exactly what kind of emotional support they need.

     

    • Be realistic about what you can do, and learn how to pass on the responsibilities to others if necessary
    • Tell people how they can help
    • Work with friends and family to make a plan of what needs to get done
    • Let go of tasks that can wait until later because you can always go back to them at another time

    Sign up for more information and resources.

    Register Now

    Indication

    What is INREBIC® (fedratinib)?

    INREBIC is a prescription medicine used to treat adults with certain types of myelofibrosis (MF). It is not known if INREBIC is safe and effective in children.


    Important Safety Information

    WARNING: ENCEPHALOPATHY INCLUDING WERNICKE’S

    What is the most important information I should know about INREBIC?
    INREBIC may cause serious side effects, including:

    • Encephalopathy (including Wernicke’s encephalopathy). A serious and sometimes fatal neurological problem called encephalopathy (including Wernicke’s encephalopathy) has happened in some people who take INREBIC.

       

      Wernicke’s encephalopathy is a neurologic emergency that can happen if you do not have enough vitamin B1 (thiamine) in your body. Your healthcare provider will do a blood test to check your vitamin B1 level before starting and during treatment with INREBIC. Your healthcare provider may tell you to stop taking INREBIC and take a vitamin B1 supplement if you develop side effects during treatment with INREBIC.

       

      Call your healthcare provider right away if you develop diarrhea, nausea, or vomiting that does not respond to treatment.

       

      Get emergency medical help right away if you develop the following:

      • confusion, memory problems, or drowsiness
      • problems with balance and movement, such as difficulty walking
      • eye problems, such as double or blurred vision or abnormal eye movements

       

      Call your healthcare provider if you experience rapid weight loss or weight loss that does not get better with treatment.

       

    Before taking INREBIC, tell your healthcare provider about all your medical conditions, including if you:

    • have low red blood cell or platelet counts
    • have or have had liver problems
    • have or have had kidney problems
    • are breastfeeding or plan to breastfeed. It is not known if INREBIC passes into your breast milk. You should not breastfeed during treatment with INREBIC and for at least 1 month after your last dose. Talk to your healthcare provider about the best way to feed your baby during treatment with INREBIC.

     

    Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

     

    INREBIC and other medicines may affect each other causing unwanted side effects. Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.

     

    How should I take INREBIC?

     

    What are the possible side effects of INREBIC?
    INREBIC can cause serious side effects, including:

     

    The most common side effects of INREBIC include:

     

    These are not all of the possible side effects of INREBIC.

     

    Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

     

    Please see full Prescribing Information, including Boxed WARNING and Medication Guide, for INREBIC.