Understand Side Effects
What’s the most important information to know about side effects?
It’s important to understand the possible side effects of treatment. Talk to your doctor about any side effects that you may experience.
INREBIC may cause serious side effects, such as encephalopathy (including Wernicke’s encephalopathy). A serious and sometimes fatal neurological problem called encephalopathy (including Wernicke’s encephalopathy) has happened in some people who take INREBIC.
Wernicke’s encephalopathy is a neurologic emergency that can happen if you do not have enough vitamin B1 (thiamine) in your body. Your healthcare provider will do a blood test to check your vitamin B1 level before starting and during treatment with INREBIC.
Your healthcare provider may tell you to stop taking INREBIC and take a B1 vitamin if you develop side effects during treatment with INREBIC.
Call your healthcare provider right away if you develop diarrhea, nausea, or vomiting that does not respond to treatment.
Get emergency medical help right away if you develop the following:
Confusion, memory problems, or drowsiness
Problems with balance and movement, such as difficulty walking
Eye problems, such as double or blurred vision or abnormal eye movements
Call your healthcare provider if you experience rapid weight loss or weight loss that does not get better with treatment.
INREBIC can cause serious side effects, including:
Low blood cell counts
INREBIC may cause low red blood cell counts (anemia) and low platelet counts (thrombocytopenia) in some people. You may need a blood transfusion if your blood counts drop too low. Your healthcare provider will do blood tests to check your blood counts before you start and during treatment with INREBIC. Tell your healthcare provider if you develop any bleeding or bruising during treatment with INREBIC.
Nausea, vomiting, and diarrhea
Your healthcare provider may give you certain medicines to help treat your nausea, vomiting, and diarrhea. Call your healthcare provider or get emergency medical help right away if you have nausea, vomiting, or diarrhea that does not get better with treatment.
Liver problems
Your healthcare provider will do blood tests to check your liver function before starting and during treatment with INREBIC.
Amylase and lipase increases
You may have changes in your blood amylase or lipase levels that may indicate a problem with your pancreas. Your healthcare provider will do blood tests to check your amylase or lipase levels before starting and during treatment with INREBIC.
The most common side effects of INREBIC include:
- Diarrhea
- Nausea
- Low red blood cell counts (anemia)
- Vomiting
These are not all the possible side effects of INREBIC. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Talk to your doctor or pharmacist about possible side effects.
